All patients

• Must have a diagnosis of psoriasis
• Perform written informed consent
• Therapy must be ongoing at the time of consent
• Must have started or switched therapy within six months of the date of consent
• Must have a PASI and DLQI within 6 months prior to patient starting therapy
• Patients should be added to the BADBIR database within 6 months of consenting

Biologic cohort

• There is no minimum PASI or DLQI score required, but scores need to be taken within six months prior to the patient commencing therapy, so we have a baseline disease severity measure.
• The biologic therapies we recruit for are:

Conventional cohort

• The patient must be naïve to biologic therapy.
• The patient's PASI at the time the drug is started must be greater than or equal to 10 (10 or more), and the DLQI greater than 10 (11 or more).
• There is no minimum PASI or DLQI score if the patient is switching between conventional therapies (less than a 3 month gap between stopping one conventional and starting another), or if the patient has an ongoing conventional treatment and is being registered on a new conventional alongside this. Although the dermatologist must deem the patient to have a history of moderate to severe psoriasis, with a score provided prior to the new conventional the patient has commenced.
• The conventional therapies we recruit for are:

Non-Biologic Small Molecule cohort

• The patient must be naïve to biologic therapy.
• There is no minimum PASI or DLQI score required, but scores need to be taken within six months prior to the patient commencing their treatment, so we have a baseline disease severity measure.
• The non-biologic small molecule therapies we recruit for are:

• Please contact the BADBIR office to discuss specific eligibility if you are unsure.